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The Link Between Medications and SJS: Understanding the Risks

Updated: Jan 7

Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are severe and potentially life-threatening blistering skin conditions. While rare, SJS and TEN can be triggered by certain medications. Here at SJS Awareness, we aim to empower you with knowledge to understand the risks.



Medications Associated with SJS/TEN:

  • Antibiotics: Sulfonamides (e.g., Bactrim, SMX-TMP) and some fluoroquinolones (e.g., Ciprofloxacin) are commonly linked to SJS/TEN.

  • Anticonvulsants: Medications like Lamotrigine (Lamictal) and Phenytoin (Dilantin) can be risk factors.

  • Pain Relievers: Nonsteroidal anti-inflammatory drugs (NSAIDs) like Ibuprofen and Naproxen carry a lower risk, but it's still important to be aware.

  • Other Medications: Certain allopurinol (gout medication) and anti-psychotic medications can also be risk factors.


It's important to remember:

  • This list is not exhaustive, and SJS/TEN can be triggered by other medications.

  • The risk of SJS/TEN is generally low, but it's important to be aware of the signs and symptoms.


Signs and Symptoms of SJS/TEN:

  • Painful flu-like symptoms (fever, chills, malaise)

  • Widespread rash with red or purple blisters (often starting on the face and genitals)

  • Burning sensation in the eyes or mouth

  • Shedding of skin on the lips, eyes, or genitals

If you experience any of these symptoms while taking medication, seek immediate medical attention!


SJS Awareness: Your Partner in SJS/TEN Education

Early diagnosis and treatment are crucial for minimizing the severity of SJS/TEN. SJS Awareness is dedicated to providing accurate information and resources. Here's what we offer:

  • Informative website: https://sjsawareness.org.uk/ provides comprehensive information about SJS/TEN, causes, and treatment options.

  • Support network: We connect patients and families affected by SJS/TEN, fostering a supportive community.

  • Raising awareness: We work with healthcare professionals and the public to raise awareness of SJS/TEN and its link to medications.


Remember: Knowledge is power. By understanding the link between medications and SJS/TEN, you can be more vigilant about your health and seek help promptly if needed.

Visit sjsawareness.org.uk today to learn more and empower yourself with knowledge.

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